The E+E accredited laboratory performs calibrations for CO₂ concentration in the range 5...300,000 ppm for all common CO₂ measuring devices such as sensors, handhelds, data loggers and spectrometers.

The calibration is performed as comparative measurement with a constant, free selectable CO₂ reference concentration generated according to DIN 51898-1. Due to the operation principle of the generator, the CO₂ reference concentration can be traced back to length, which is a fundamental physical quantity of the International System of Units (SI). Therefore, the E+E CO₂ reference generator is a primary standard.

According to the International Laboratory Accreditation Cooperation (ILAC) agreements, only calibration laboratories accredited according to EN ISO/IEC 17025 can ensure the traceability of measurement results to SI and their full international comparability. The accredited calibration certificate states the measurement uncertainty associated to the specific calibration process.

Accredited CO₂ calibration certificates are generally required for measuring devices used for safety or for the control of key manufacturing processes. Accredited CO₂ calibrations are of interest for instance in the Food and Drugs Administration (FDA) regulated industries such as food and pharmaceutical. Reliable CO₂ monitoring and control is paramount for biological incubators. In building automation, the accuracy of CO₂ measuring devices impacts directly on the efficiency of demand controlled ventilation systems.